If you’re looking for supplements with the same ingredients as expensive brands, the price tag doesn’t always match the quality inside the bottle.. Many “premium” products share the exact same ingredients, forms, and dosages as much cheaper options. If you know how to read a label, you can cut your costs in half without losing a single benefit.
Here are 7 supplements where the less expensive brand delivers the exact same thing as the pricey version — same actives, same potency, just without the marketing markup.
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1) CoQ10 (Ubiquinol)
- Expensive Brand: Healthy Origins Ubiquinol, 100 mg softgels
- Affordable Brand: Qunol Mega Ubiquinol, 100 mg softgels
Why they match:
Both supply the reduced, active form of CoQ10 — ubiquinol — at the same dose per softgel. Both are oil-based for better absorption and made in GMP-certified facilities. The only real difference is the label and the price.
Savings potential: Often 30–50% cheaper per 100 mg with the affordable brand.
2) N-Acetyl-L-Cysteine (NAC)
- Expensive Brand: Life Extension NAC, 600 mg capsules
- Affordable Brand: NOW NAC, 600 mg capsules
Why they match:
Same molecule, same 600 mg dose, same capsule form. Both are designed for antioxidant and liver support, both third-party tested.
Savings potential: Large-count bottles of the affordable brand can save 40–70% over the expensive one.
3) Creatine Monohydrate
- Expensive Brand: Optimum Nutrition Micronized Creatine, 5 g per scoop
- Affordable Brand: Bulk Supplements Creatine Monohydrate, 5 g per scoop
Why they match:
Pure creatine monohydrate in both cases — the gold-standard form studied for strength and muscle performance. Micronized simply means it mixes more easily; it doesn’t change the effect.
Savings potential: Bulk powder drops cost to pennies per serving.
4) Vitamin D3 (5,000 IU)
- Expensive Brand: Thorne D-5000, 125 mcg (5,000 IU) per capsule
- Affordable Brand: NOW Vitamin D3, 125 mcg (5,000 IU) softgels
Why they match:
Identical vitamin form (cholecalciferol) and potency. Both are oil-based for absorption and made in quality-controlled facilities.
Savings potential: Expect 30–60% savings per dose with the affordable brand.
5) Magnesium Glycinate
- Expensive Brand: Pure Encapsulations Magnesium Glycinate, 120 mg elemental per tab
- Affordable Brand: NOW Magnesium Bisglycinate, 100 mg elemental per capsule
Why they match:
Both use Albion TRAACS® chelated magnesium for better absorption and fewer digestive issues. Same elemental magnesium content per serving.
Savings potential: Roughly 50% cheaper for the same amount of magnesium.
6) Berberine HCl (500 mg)
- Expensive Brand: Nature’s Truth Berberine HCl, 500 mg capsules
- Affordable Brand: Best Naturals Berberine HCl, 500 mg capsules
Why they match:
Same berberine hydrochloride form, same 500 mg dose. Both are made for metabolic and cardiovascular support.
Savings potential: Typically 30–60% less per capsule.
7) Melatonin (5 mg)
- Expensive Brand: Pure Encapsulations Melatonin, 3 mg tablets
- Affordable Brand: Nutricost Melatonin, 3 mg tablets
Why they match:
Same hormone, same 5 mg strength, same intended use for occasional sleep support. No difference in the active ingredient or dose.
Savings potential: Often half the cost per tablet.

How to Spot Your Own Affordable Matches
- Match the exact form (e.g., ubiquinol vs. ubiquinone; glycinate vs. oxide).
- Match the dose per serving — and check serving size carefully.
- Ignore flashy words like “ultra,” “micronized,” or “doctor-formulated.”
- Look for quality seals like USP, NSF, or “third-party tested.”
- Check for filler overload — more isn’t better if it’s just fluff.
Bottom Line
By matching the active ingredient, form, and dosage, you can get the same benefits without paying for a premium label. The seven supplements above prove you can slash your supplement bill without sacrificing results. Always read labels, compare, and buy smart.
For further reading: How to Start Taking Supplements: A Beginner’s Blueprint